目的 对北京地区汉族人群遗传数据进行调查研究。方法 利用PCR自动化检测技术检测中国北京地区汉族人群D1S1656，D10S2325，D11S2368， D12S391，D14S1434及GATA198B05共6个STR基因座的遗传多态性，获得6个STR基因座的群体遗传学数据，评价其法医学应用价值。结果 6个STR基因座的个体鉴别力（Discrimination power，DP）在09777～08769之间，多态性信息含量（Polymorphism information content，PIC）在06867～08801之间，杂合度（Heterozygosity，H）在07219～08684之间，非父排除率（Probability of paternity exclusion, PE）在04456～06793之间，累积个体鉴别力为099999997，累积非父排除率为0995765192 。结论6个STR基因座等位基因频率分布均匀，多态性高，适用于法医学亲子鉴定及个人识别，可作为现有基因座的补充。

To investigate the genetic polymorphism of D1S1656,D10S2325,D11S2368, D12S391，D14S1434，GATA198B05 in Chinese Han population of Beijing, PCR method was used. All allele frequencies, heterozygosity (H), discrimination power(DP), exclusion of paternity probability(PE) and polymorphism information content(PIC) were calculated. The DP is at 09777～08769 , PIC is at 06867～08801, H is at 07219～08684, PE is at 04456～06793 According to the results obtained in this study, it is suggested that D1S1656，D10S2325，D11S2368， D12S391，D14S1434 and GATA198B05 were useful genetic markers for individual identification and paternity testing in forensic science and they were complementary to general loci.