DI Yu-min,ZHU Jun,CHANG Jing
Forensic Science And Technology. 2010, 0(1): 3.
Abstract (
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Objective To provide a extraction,purification and instrumental analysis method for the determination of basic abuse drugs in decay organism samples.Methods Abuse drugs extracted from organism samples by liquid-liquid and solid phase extraction were detected and quantified with GC/MS and GC/NPD.Using cyclohexane as the extracted solvent。and the Bond-Elut Certify cartridge columns were washed with methanol,and eluted by dichloromethane:isopropyl alcohol:ammonium hydmxide (78:20:2,v/v/v)mixed solvent.Results The morphine。codeine,estazolam and promethazine were all simultaneously detected from liver,stomach,heart blood and urine of the dead.And the drug concentration in Iiver was morphine 0.094μ9/g,codeine 0.257μg/g,and promethazine 0.110μg/g,in urine was morphine 0.334μ9/ml,codeine 4.054μg/ml,and promethazine 0.066μ9/ ml,and in heart blood was morphine 0.036μg/ml,codeine 0.106μg/mL,and promethazine 0.088μg/mL Conclution This method is nicety,reliable,and scientific,and it can be used in the analysis of kinds of basic drugs in organism samples in forensic toxicology.