Genetic Polymorphism of 19 STR Loci in Han Population in Jincheng

LIU Yanjun, HE Xiaohua, GONG Zhigang, LI Lin, WANG Bing, ZHANG Tianlin

Forensic Science and Technology ›› 2015, Vol. 40 ›› Issue (4) : 330-331. DOI: 10.16467/j.1008-3650.2015.04.018
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Genetic Polymorphism of 19 STR Loci in Han Population in Jincheng

  • LIU Yanjun1, 2, HE Xiaohua2, GONG Zhigang2, LI Lin2, WANG Bing2, ZHANG Tianlin2, *
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Abstract

The genetic polymorphism of 19 short tandem repeats (STR) loci in Han population in Jincheng Shanxi was studied using Goldeneye 20A STR Amplification Kit. 1233 unrelated individuals were investigated to obtain allele frequencies and forensic genetic data. No deviations of allelic frequency from Hardy-Weinberg equilibrium were observed (P>0.05). Heterozygosity (H) of 19 loci ranges from 0.639 to 0.919,matching probability (PM) 0.014 to 0.177; power of discrimination (DP) 0.806 to 0.987; polymorphism information content (PIC) 0.58~0.91; power exclusion (PE) 0.342~0.821.The cumulative discrimination power (CDP) and cumulative probability of exclusion (CPE) are 1-1.27×10-23 and 0.999999991, respectively. The result indicates that 19 STR loci are highly polymorphic and suitable for forensic personal identification and paternity testing in this area.

Key words

forensic genetics / genetic polymorphism / short tandem repeats (STR) / gene locus / Jincheng Han population

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LIU Yanjun, HE Xiaohua, GONG Zhigang, LI Lin, WANG Bing, ZHANG Tianlin. Genetic Polymorphism of 19 STR Loci in Han Population in Jincheng. Forensic Science and Technology. 2015, 40(4): 330-331 https://doi.org/10.16467/j.1008-3650.2015.04.018

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